
Ulcerative Colitis
Comprehensive Care by Dr. Kushan Kaushik Sengupta – Renowned Consultant Gastroenterologist in Kolkata
Ulcerative Colitis (UC) is a chronic type of Inflammatory Bowel Disease (IBD) that causes long-standing inflammation and ulcer formation in the lining of the large intestine (colon) and rectum. It typically develops gradually and is characterized by alternating periods of flare-ups and remission. If untreated, Ulcerative Colitis can severely impact daily life and may lead to serious complications.
Dr. Kushan Kaushik Sengupta, a highly experienced Consultant Gastroenterologist, Hepatologist & Interventional Endoscopist, is widely regarded as one of the best Gastroenterologists in Kolkata for managing complex digestive disorders such as Ulcerative Colitis. His expertise in advanced diagnostics, targeted treatments, and long-term disease management ensures patients receive personalized, effective, and compassionate care.
Understanding Ulcerative Colitis
Ulcerative Colitis occurs when the immune system mistakenly attacks the colon’s lining, leading to continuous inflammation and ulceration. While the exact cause remains unknown, several contributing factors have been identified:
Genetic predisposition
Immune system dysfunction
Imbalance of gut microbiota
Lifestyle and environmental factors
Stress and dietary triggers (worsening flare-ups)
Symptoms vary depending on the extent and severity of inflammation. Typical signs include:
Persistent diarrhea (often with blood or mucus)
Abdominal cramping and pain
Urgency to pass stool
Rectal bleeding
Weight loss and loss of appetite
Fatigue and weakness
Fever during flare-ups
Anemia due to chronic blood loss
Dehydration and electrolyte imbalance
In severe cases, sudden severe abdominal pain or bloating
Early medical evaluation is essential to avoid complications such as severe bleeding, toxic megacolon, or colorectal cancer.
Common Signs & Symptoms


Diagnostic Procedures
Dr. Kushan Kaushik Sengupta follows a comprehensive and systematic diagnostic approach to confirm Ulcerative Colitis and assess disease severity.
Diagnostic evaluations include:
Detailed Clinical History & Physical Examination
Assessment of symptom duration, pattern, triggers, and overall health.
Blood Tests
To detect anemia, infection, or signs of inflammation (CRP, ESR).
Stool Tests
Calprotectin and other markers to differentiate UC from infections or other forms of IBD.
Colonoscopy with Biopsy
The gold standard to visualize inflammation, ulcers, and obtain tissue samples for accurate diagnosis.
Sigmoidoscopy
Useful for evaluating inflammation limited to the lower colon.
CT / MRI Enterography
Advanced imaging to assess complications such as severe inflammation, perforation, or toxic megacolon.
With precise evaluation and staging, Dr. Sengupta ensures each patient receives a targeted and evidence-based treatment plan.






Treatment Options for Ulcerative Colitis
While Ulcerative Colitis cannot be completely cured, modern treatments make it possible to manage symptoms, achieve remission, and improve long-term outcomes.
Medical Management
Aminosalicylates (5-ASA):
First-line treatment to reduce inflammation in mild to moderate UC.
Corticosteroids:
Used for short-term control during acute flare-ups.
Immunosuppressants:
Medications like Azathioprine or Cyclosporine to suppress immune overactivity.
Biologic Therapy:
Advanced targeted drugs (Anti-TNF agents, Anti-integrin therapy, JAK inhibitors) for moderate to severe UC.
Antibiotics:
Prescribed when infections or complications are suspected.
Nutritional & Lifestyle Therapy
Personalized diet plans to avoid trigger foods
Management of nutritional deficiencies
Guidance on hydration, stress control, and gut-friendly habits
Endoscopic & Interventional Care
As a skilled Interventional Endoscopist, Dr. Sengupta performs advanced procedures to manage complications such as strictures, bleeding, or severe inflammation.
Surgical Management
Surgery is considered when medical treatment fails or complications arise (such as perforation, severe bleeding, or cancer risk).
Dr. Sengupta works closely with expert GI surgeons to ensure safe, coordinated, and seamless care.






Why Choose Dr. Kushan Kaushik Sengupta for Ulcerative Colitis Care in Kolkata?
Renowned Consultant Gastroenterologist, Hepatologist & Interventional Endoscopist
Highly experienced in managing complex IBD cases, including Ulcerative Colitis and Crohn’s Disease
Expert in advanced diagnostics such as colonoscopy, capsule endoscopy & imaging-based evaluations
Comprehensive treatment combining medicine, endoscopy, nutrition, and long-term monitoring
Patient-first care philosophy with clear communication and compassionate support
Widely recognized as one of the best Gastroenterologists in Kolkata for digestive and liver disorders